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Tamoxifen treatment for pubertal gynecomastia

By Derman O, Kanbur NO, Kutluk T.
Section of Adolescent Medicine, Department of Pediatrics,
Hacettepe University Faculty of Medicine, 06100 Ankara-Turkey.

We evaluated the efficacy of the tamoxifen treatment in 37 patients with pubertal gynecomastia. All had distinct, easily palpable breast swellings with a diameter of over three cm. Pain, tenderness, and swelling associated with gynecomastia were reported by six patients. Eight of the patients were obese. One patient also suffered from varicocele. Pain and size reduction was seen in all patients with tamoxifen treatment. No long-term side effects of tamoxifen were observed. The dose of tamoxifen was increased in three patients due to poor response. Two of the treatment group had recurrence problem at follow-up. We did not need to refer any patient to surgery. Tamoxifen treatment is relatively non-toxic, may be beneficial and we think it should be considered for pubertal gynecomastia.

Excellent page of medical information about gynecomastia.

http://ourworld.compuserve.com/homepages/L_Lindsey/4320006.htm

Texts

Plastic and Reconstructive Surgery of the Breast. Little, Brown, and Co. 1976. 305-327. Author : Robert M. Goldwyn.

Plastic and Reconstructive Surgery of the Breast. Ed. by R. Barrett Noone. Pub by B. C. Decker 1991. p. 98-116.

Journal Articles:

Huang, Hidalgo, + Lewis. A Circumareolar Approach in Surgical Management of Gynecomastia. Plastic and Reconstructive Surgery. January 1982. p. 35-40.

Samdal, Kleppe, Amland, + Abyholm. Surgical Treatment of Gynecomastia: Five Years' Experience with Liposuction. Scandanavian Journal of Plastic and Reconstructive Hand Surgery. June 1994, p. 123-30.

Kornstein, Cinelli. Inferior Pedicle Reduction Technique for Larger Forms of Gynecomastia. Aesthetic Plastic Surgery. Fall 1992. p.331-5.

Ward, Khalid. Surgical Treatment of Grade III Gynaecomastia. Annals of the Royal College of Surgeons of England. July 1989. p. 226-8.

Courtiss. Gynecomastia: Analysis of 159 Patients and Current Recommendations for Treatment. Plastic Reconstructive Surgery, 1987, (vol?) 79. p. 740-50.

Simon, Hoffman, + Kahn. Classification and Surgical Correction of Gynecomastia. Plastic and Reconstructive Surgery. January 1973. p. 48-52.

Brenner, Berger, Schneider, Axmann. Male Reduction Mammoplasty in Serious Gynecomastias. Aesthetic Plastic Surgery. Fall 1992. p. 325-30.

Botta. Alternatives for the Surgical Correction of Severe Gynecomastia. Aesthetic Plastic Surgery. Jan/Feb 1998. p. 65-7.

Neuman. Evaluation and Treatment of Gynecomastia. American Family Physician. April 1997. p. 1835-1847.

Recent Medical Articles

New article from Health and Science

Because the article link may not work in future and the site requires registration, we have provided a pdf of the article here.


Gynecomastia and transgender article
..." reviews a wide sample of papers describing gynecomastia, its occurrence in metabolic disorders, and its presence in case vignettes or biographies of transgender biological males."
Click here to read!


Article on Breast Cancer In Men
Click here to read!


Article on Merle Yost from Surgery News,
Click here to view the full article.


Newly discovered mutations possibly linked to breast cancer
Click here to view the full article.


Nursing Fathers
http://www.unhinderedliving.com/nursingfather.html


Aromatase and gynecomastia
An article on Aromatase and gynecomastia has recently been discovered. Obviously, we can't publish it for copyright reasons, but here's the link : http://journals.endocrinology.org/erc/006/erc0060315.htm
Note: You'll need Adobe Acrobat to read the .pdf file.


Pubmed study
A new pubmed study has been released showing the difference in recurrences depending on the removal procedure used. Check it out : here!